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What's New > PEHSU Journal Club | Environmental Uranium Exposure from Drinking Water - February 15, 2017 at 1pm EST

PEHSU Journal Club | Environmental Uranium Exposure from Drinking Water - February 15, 2017 at 1pm EST

posted on Feb 7, 2017

Learning Objectives:

At the conclusion of this activity, attendees should be able to:
  • Describe current permissible exposure limits for uranium in drinking water
  • Describe the absorption, distribution, and elimination of ingested uranium
  • Review the potential effects, if any, of ingested uranium on the renal system
  • Review the potential for development of renal or bladder malignancies after long-term exposure to uranium in drinking water
  • Describe current testing options and recommendations for patients who may have been exposed to uranium in drinking water
  • Briefly discuss possible treatment options for uranium exposure

Articles to be discussed:

1. Kurttio, P., Harmoinen, A., Saha, H., Salonen, L., Karpas, Z., Komulainen, H., & Auvinen, A. (2006). Kidney toxicity of ingested uranium from drinking water. American journal of kidney diseases, 47(6), 972-982.

2. Kurttio, P., Salonen, L., Ilus, T., Pekkanen, J., Pukkala, E., & Auvinen, A. (2006). Well water radioactivity and risk of cancers of the urinary organs. Environmental research, 102(3), 333-338.

3. Orloff, K. G., Mistry, K., Charp, P., Metcalf, S., Marino, R., Shelly, T., Melaro, E., Donohoe, A. M., & Jones, R. L. (2004). Human exposure to uranium in groundwater. Environmental research, 94(3), 319-326.

4. Seldén, A. I., Lundholm, C., Edlund, B., Högdahl, C., Ek, B. M., Bergström, B. E., & Ohlson, C. G. (2009). Nephrotoxicity of uranium in drinking water from private drilled wells. Environmental research, 109(4), 486-494.

Presented By: Keith Baker, MD

Baker_021517
Keith Baker, MD
Medical Toxicology Fellow
Rocky Mountain Poison and Drug Center
Denver, CO
Region 8 PEHSU